Finite Element Modelling of Pulsatile Blood Flow in Idealized Model of Human Aortic Arch: Study of Hypotension and Hypertension
نویسندگان
چکیده
A three-dimensional computer model of human aortic arch with three branches is reproduced to study the pulsatile blood flow with Finite Element Method. In specific, the focus is on variation of wall shear stress, which plays an important role in the localization and development of atherosclerotic plaques. Pulsatile pressure pulse is used as boundary condition to avoid flow entry development, and the aorta walls are considered rigid. The aorta model along with boundary conditions is altered to study the effect of hypotension and hypertension. The results illustrated low and fluctuating shear stress at outer and inner wall of aortic arch, proximal wall of branches, and entry region. Despite the simplification of aorta model, rigid walls and other assumptions results displayed that hypertension causes lowered local wall shear stresses. It is the sign of an increased risk of atherosclerosis. The assessment of hemodynamics shows that under the flow regimes of hypotension and hypertension, the risk of atherosclerosis localization in human aorta may increase.
منابع مشابه
An advection-diffusion multi-layer porous model for stent drug delivery in coronary arteries
Arterial drug concentration distribution determines local toxicity. The safety issues dealt with Drug-Eluting Stents (DESs) reveal the needs for investigation about the effective factors contributing to fluctuations in arterial drug uptake. The current study focused on the importance of hypertension as an important and controversial risk factor among researchers on the efficacy of Heparin-Eluti...
متن کاملBlood Flow Simulation in an Aorta with a mild coarctation Using Magnetic Resonance Angiography and Finite Volume Method
Coarctation of the aorta is one of the five main congenital cardiovascular failures, accounting for 6–8 percent of these failures. This research aimed to simulate the blood flow of a seventeen-year-old male teen with a mild coarctation at one-third of his aorta's descending branch. The simulation was performed by extracting the domain and the input pulsatile velocity signal as the boundary cond...
متن کاملEvaluating the effect of stenosis increase and pulsatile blood pressure on effective stress distribution in viscoelastic finite element model based on carotid artery ultrasound images
The aim of this study is to evaluate the changes of effective stress distribution in plaque by progressing to the stenosis throat and to assess the pulsatile pulse pressure effect on effective stress of a viscoelastic finite-element model of carotid arteries having less and more than 50% stenosis. In-vivo geometries of the arteries were reconstructed using consecutive transverse ultrasound imag...
متن کاملNewtonian and Non-Newtonian Blood Flow Simulation after Arterial Stenosis- Steady State and Pulsatile Approaches
Arterial stenosis, for example Atherosclerosis, is one of the most serious forms of arterial disease in the formation of which hemodynamic factors play a significant role. In the present study, a 3-D rigid carotid artery with axisymmetric stenosis with 75% reduction in cross-sectional area is considered. Laminar blood flow is assumed to have both Newtonian and non-Newtonian behavior (generalize...
متن کاملManagement of anesthesia in a patient with ruptured abdominal aortic aneurysm: A case report
Introduction: Abdominal aortic aneurysm is a multifactorial condition which associated with aging and atherosclerosis. During aneurysm surgery, hypotension after aortic clamp removing occure commonly that require specific treatments. This case report showes administration of blood and hemodynamic control methods after aortic unclumping during aortic aneurysm surgery. Patient: A 75–years-o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012